M Maliepaard Selected Research

Mitoxantrone (Novantrone)

9/2002	Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
10/2000	Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan.
5/2000	Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone- and topotecan-resistant cell lines.

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M Maliepaard Research Topics

Disease

8	Breast Neoplasms (Breast Cancer) 09/2002 - 01/2000
6	Neoplasms (Cancer) 09/2002 - 01/2000
2	Ovarian Neoplasms (Ovarian Cancer) 09/2002 - 01/2000
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2003
1	Head and Neck Neoplasms (Head and Neck Cancer) 09/2001
1	Colorectal Neoplasms (Colorectal Cancer) 01/2001
1	Glioblastoma (Glioblastoma Multiforme) 01/2001
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2000

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 09/2002 - 01/2000
5	Topotecan (Hycamtin)FDA LinkGeneric 09/2002 - 01/2000
4	Pharmaceutical PreparationsIBA 01/2001 - 01/2000
3	Irinotecan (Camptosar)FDA LinkGeneric 09/2002 - 01/2000
3	Mitoxantrone (Novantrone)FDA LinkGeneric 09/2002 - 05/2000
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 11/2001 - 05/2000
2	Cisplatin (Platino)FDA LinkGeneric 03/2003 - 09/2001
2	ElacridarIBA 09/2002 - 04/2001
2	multidrug resistance-associated protein 1IBA 09/2002 - 05/2000
2	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2002 - 10/2000
2	Messenger RNA (mRNA)IBA 09/2002 - 05/2000
2	Daunorubicin (Cerubidine)FDA LinkGeneric 11/2001 - 10/2000
2	Adenosine Triphosphate (ATP)IBA 10/2000 - 01/2000
1	Etoposide (VP 16)FDA LinkGeneric 03/2003
1	exatecan (DX 8951f)IBA 09/2002
1	CamptothecinIBA 09/2002
1	Cell Surface ReceptorsIBA 01/2001
1	Tyrosine Kinase InhibitorsIBA 01/2001
1	Canertinib (CI 1033)IBA 01/2001
1	Monoclonal AntibodiesIBA 05/2000
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2000
1	Topoisomerase I InhibitorsIBA 01/2000
1	9-aminocamptothecinIBA 01/2000

Therapy/Procedure

1	Therapeutics 03/2003